Skip to main content

Table 1 Low 185 passage whole genome sequencing

From: A long-term surviving patient with recurrent low-grade serous ovarian carcinoma treated with the MEK1/2 inhibitor, selumetinib

  Tumor DNA Blood DNA  
Gene Amino acid change Mutant allele reads Wild-type allele reads Frequency of mutant allele Mutant allele reads Wild-type allele reads Frequency of mutant allele Functional impact
CCDC110 P209Q 7 9 44 0 8 0 Neutral
FAT1 Q2933P 6 6 50 0 6 0 Neutral
PCDHGA1 A443T 7 6 54 0 5 0 Neutral
USP45 K67E 6 6 50 0 5 0 Medium
RP1L1 Q1861P 5 7 42 0 9 0 Neutral
PLBD1 L25delL 7 7 50 0 9 0 Neutral
KRAS G12V 8 11 42 0 9 0 Medium
KRT84 I206V 11 4 73 0 3 0 Neutral
ADAMTS17 N1094S 6 7 46 0 8 0 Neutral
ADAM33 M764T 7 9 44 0 4 0 Low