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Table 3 Obstetrical outcomes after radical trachelectomy (where N > 50 reported)

From: Fertility-sparing management in cervical cancer: balancing oncologic outcomes with reproductive success

Study

Successful fertility sparing management#

Attempted to conceive

Conceptions

T1/T2 losses

Live births (ongoing pregnancy)

Median follow up months for entire series (range)

Bernardini 2003 [114]

80

39

22

4

18

–

Hertel 2006 [29]

106

–

18

3

12 (3)

29 (1–128)

Shepherd 2006 [108]

112

63

55

–

28 (3)

45a (1–120)

Li 2011 [53]

56

10

2

0

1 (1)

23 (1–78)

Plante 2011 [57]

110

–

106

29

77

95 (4–225)

Kim 2012 [115]

77

35

27

7

20

–

Wethington 2012 [110]

70

38

31

9

16 (6)

32 (1–124)

Cao 2013 [51]

150

77

20

9

14

25 (6–91)

Nishio 2013 [116]

114

69

31

5

21 (5)

33

Vieira 2015 [113]

83

34

19

5

10 (4)

51 (10–147)

Hauerberg 2015 [112]

108

72

77

21

53 (3)

55.7 (5.5–147)

Kasuga 2016 [117]

172

109

61

13

43 (5)

–

Total

1238

546

469

105

313 (30)

 

Crude rates

(%)

   

TI/T2 loss rate = 22.4 %

Live birth rate = 66.7 % &

 
  1. Abbreviations: T1 first trimester, T2 second trimester
  2. aOnly mean follow up is reported
  3. #Excludes those who had completion hysterectomy, or received fertility-compromising adjuvant treatment
  4. & Does not include ongoing pregnancies