Fertility-sparing management in cervical cancer: balancing oncologic outcomes with reproductive success

Table 4 Oncologic outcomes of radical trachelectomy for lesions ≥ 2 cm (where N > 10 reported)

Study	N with lesions ≥ 2 cm who underwent fertility sparing surgery	Approach	N recurrences (mos)	N dead of disease (mos)	Median follow up months for entire series (range)
Marchiole 2007 [109]	21	LAVRT	6 (7, 11, 18, 20, 21, 93)	4 (21, 24, 27, 41)	95 (31–234)
Nishio 2009 [118]	13	ART	5 (4, 8, 14, 18, 23)	0	27 (1–67)
Cao 2013 [51]	48	VRT ART	5 (−)	2 (−)	34.3^a
Li 2013 [119]	61	ART	0	0	30 (2–108)
Lintner 2013 [120]	31	ART	4 (5, 6, 10, 14)	2 (16, 22)	90 (60–148)
Wethington 2013 [121]	15	ART LAVRT VRT	1 (9)	0	44 (1–90)
Total	N = 189		N = 21	N = 8
Crude rates (%)			Recurrence rate = 11.1 %^#	Mortality rate = 4.2 %^#

Abbreviations: LAVRT laparoscopic-assisted vaginal radical trachelectomy, ART abdominal radical trachelectomy, VRT vaginal radical trachelectomy
^aOnly mean follow up is reported
^#Crude recurrence and mortality rates among those who successfully underwent fertility sparing surgery, notwithstanding adjuvant treatment received

ISSN: 2053-6844