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Table 6 Oncologic outcomes of non-radical fertility sparing procedures (where N > 10 reported)

From: Fertility-sparing management in cervical cancer: balancing oncologic outcomes with reproductive success

Study

N eligible

Surgical procedure (includes pelvic LN assessment)

Successful fertility sparing surgery

N recurrences (mos)

N dead of disease (mos)

Median follow up months for entire series (range)

Bisseling 2007 [122]

18

18 cone

18

0

0

72a

Rob 2007 [123]

26

15 ST

7 cone

20

1 (14)

0

49 (18–84)

Landoni 2007 [124]

11

11 cone

11

0

0

20 (7–29)

Fagotti 2011 [125]

17

17 cone

13

0

0

16 (8–101)

Maneo 2011 [126]

36

36 cone

31

3 (20, 34, 36)

1 (72)

66 (18–168)

Raju 2012 [127]

15

15 ST

15

0

0

96 (12–120)

Palaia 2012 [128]

14

14 ST

14

0

0

38 (18–96)

Plante 2013 [129]

16

16 ST

16

0

0

27 (1–65)

Andikyan 2014 [130]

10

9 cone

1 cx bx

9

0

0

17 (1–83)

Bouchard-Fortier 2014 [55]

29

29 cone

29

0

0

21 (1–112)

Salihi 2015 [131]

11

11 cone

9

1 (40)

0

58 (13–122)

Total

203

138 Cone

60 ST

185

N = 5

N = 1

 

Crude rates (%)

   

Recurrence rate = 2.7 %#

Mortality rate = 0.5 %#

 
  1. Abbreviations: ST simple trachelectomy, cx bx cervical biopsy
  2. aOnly mean follow up is reported
  3. #Crude recurrence and mortality rates among those who successfully underwent fertility sparing surgery, notwithstanding adjuvant treatment received