Skip to main content

Table 6 Oncologic outcomes of non-radical fertility sparing procedures (where N > 10 reported)

From: Fertility-sparing management in cervical cancer: balancing oncologic outcomes with reproductive success

Study N eligible Surgical procedure (includes pelvic LN assessment) Successful fertility sparing surgery N recurrences (mos) N dead of disease (mos) Median follow up months for entire series (range)
Bisseling 2007 [122] 18 18 cone 18 0 0 72a
Rob 2007 [123] 26 15 ST
7 cone
20 1 (14) 0 49 (18–84)
Landoni 2007 [124] 11 11 cone 11 0 0 20 (7–29)
Fagotti 2011 [125] 17 17 cone 13 0 0 16 (8–101)
Maneo 2011 [126] 36 36 cone 31 3 (20, 34, 36) 1 (72) 66 (18–168)
Raju 2012 [127] 15 15 ST 15 0 0 96 (12–120)
Palaia 2012 [128] 14 14 ST 14 0 0 38 (18–96)
Plante 2013 [129] 16 16 ST 16 0 0 27 (1–65)
Andikyan 2014 [130] 10 9 cone
1 cx bx
9 0 0 17 (1–83)
Bouchard-Fortier 2014 [55] 29 29 cone 29 0 0 21 (1–112)
Salihi 2015 [131] 11 11 cone 9 1 (40) 0 58 (13–122)
Total 203 138 Cone
60 ST
185 N = 5 N = 1  
Crude rates (%)     Recurrence rate = 2.7 %# Mortality rate = 0.5 %#  
  1. Abbreviations: ST simple trachelectomy, cx bx cervical biopsy
  2. aOnly mean follow up is reported
  3. #Crude recurrence and mortality rates among those who successfully underwent fertility sparing surgery, notwithstanding adjuvant treatment received