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Table 9 Obstetrical outcomes of fertility-sparing surgery after NACT (where N > 5 reported)

From: Fertility-sparing management in cervical cancer: balancing oncologic outcomes with reproductive success

Study Successful fertility sparing management# Conceptions T1/T2 losses Live births (ongoing) Median follow up months for entire series (range)
Maneo 2008 [65] 16 10 1 9 69 (10–124)
Robova 2010 [132] 12 7 0 6 (1) 76.5 (17–142)
Marchiole 2011 [64] 7 1 0 0 (1) 22 (5–49)
Lanowska 2014 [134] 18 7 2 4 (1) 23 (1–88)
Salihi 2015 [131] 9 11 4 7 58 (13–122)
Total 62 36 7 26 (3)  
Crude rates (%)    19.4 % T1/T2 loss rate 72.2 % live birth rate  
  1. Abbreviations: T1 first trimester, T2 second trimester
  2. #Excludes those who had completion hysterectomy, or received fertility-compromising adjuvant treatment
  3. & Does not include ongoing pregnancies