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Table 9 Obstetrical outcomes of fertility-sparing surgery after NACT (where N > 5 reported)

From: Fertility-sparing management in cervical cancer: balancing oncologic outcomes with reproductive success

Study

Successful fertility sparing management#

Conceptions

T1/T2 losses

Live births (ongoing)

Median follow up months for entire series (range)

Maneo 2008 [65]

16

10

1

9

69 (10–124)

Robova 2010 [132]

12

7

0

6 (1)

76.5 (17–142)

Marchiole 2011 [64]

7

1

0

0 (1)

22 (5–49)

Lanowska 2014 [134]

18

7

2

4 (1)

23 (1–88)

Salihi 2015 [131]

9

11

4

7

58 (13–122)

Total

62

36

7

26 (3)

 

Crude rates (%)

  

19.4 % T1/T2 loss rate

72.2 % live birth rate

 
  1. Abbreviations: T1 first trimester, T2 second trimester
  2. #Excludes those who had completion hysterectomy, or received fertility-compromising adjuvant treatment
  3. & Does not include ongoing pregnancies