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Table 2 In Vitro Tumor Responses to Seven Drugs

From: Analysis of in vitro chemoresponse assays in endometrioid endometrial adenocarcinoma: an observational ancillary analysis

Assay Resultb

Drug

Tumor Grade

No. patients

R (%)

I (%)

S (%)

P valuea

Carboplatin

     

.928

1

25

28.0

40.0

32.0

 

2

41

24.4

39.0

36.6

 

3

66

19.7

53.0

27.3

 

Cisplatin

     

.322

1

24

29.2

41.7

29.2

 

2

43

18.6

55.8

25.6

 

3

67

13.4

58.2

28.4

 

Docetaxel

     

.812

1

19

26.3

42.1

31.6

 

2

35

8.6

54.3

37.1

 

3

61

18.0

47.5

34.4

 

Doxorubicin

     

.080

1

27

18.5

55.6

25.9

 

2

48

25.0

56.3

18.8

 

3

77

7.8

61.0

32.2

 

Gemcitabine

     

.238

1

14

28.6

28.6

42.9

 

2

26

30.8

23.1

46.2

 

3

45

22.2

62.2

15.6

 

Paclitaxel

     

.670

1

24

33.3

33.3

33.3

 

2

40

15.0

37.5

47.5

 

3

65

15.4

53.9

30.8

 

Topotecan

     

.861

1

22

27.3

45.5

27.3

 

2

41

24.4

48.8

26.8

 

3

61

23.0

50.8

26.2

 
  1. aCorrelation of tumor grade with assay result examined by Cochran-Armitage test
  2. b R resistant, I intermediately sensitive, S sensitive