Table 1 Summary of patient characteristics
Patient Demographics | Gem/Cis Overall | Gem/Carbo Overall | Gem-]/Cis Plt Sensitive | Gem/Carbo Plt Sensitive | Gem/Cis Plt Resistant | Gem/Carbo Plt Resistant |
|---|---|---|---|---|---|---|
N = 21 | N = 27 | N = 10 | N = 18 | N = 10 | N = 8 | |
Mean Age [# ± SD (Range)] | 61.4 [±10.2(42–84)] | 62.0 [+9.1(43–79)] | 60.8 [+9.4(49–81)] | 60.8 [+8.3(47–79)] | 61.6 [+11.9(42–84)] | 65.8 [+10.7(43–78)] |
Race | ||||||
-White | 16 | 20 | 7 | 14 | 8 | 5 |
-Hispanic | 3 | 4 | 2 | 3 | 1 | 1 |
-African American | 0 | 1 | 0 | 0 | 0 | 1 |
-Asian | 0 | 1 | 0 | 1 | 0 | 0 |
-Unreported race | 2 | 0 | 1 | 0 | 1 | 1 |
Mean # of Comorbidities | 1.48 | 1.48 | 0.70 | 1.11 | 2.30 | 2.50 |
Tumor Histology | ||||||
-Serous | 15 | 17 | 8 | 11 | 6 | 6 |
-Clear Cell | 0 | 1 | 0 | 1 | 0 | 0 |
-Adenocarcinoma | 2 | 2 | 2 | 0 | 0 | 1 |
-Mixed | 1 | 3 | 0 | 3 | 1 | 1 |
-Unreported histology | 3 | 3 | 0 | 3 | 3 | 0 |
Tumor Stage | ||||||
-I | 0 | 1 | 0 | 0 | 0 | 1 |
-II | 2 | 1 | 2 | 0 | 0 | 0 |
-III | 12 | 17 | 5 | 11 | 6 | 5 |
-IV | 3 | 3 | 2 | 3 | 1 | 0 |
-Unreported stage | 4 | 6 | 1 | 4 | 3 | 2 |
Tumor Debulking | ||||||
-Optimal (<1 cm) | 10 | 16 | 5 | 11 | 5 | 4 |
-Suboptimal | 5 | 7 | 2 | 6 | 2 | 1 |
-Not a surgical candidate | 0 | 1 | 0 | 0 | 0 | 1 |
-Unreported tumor debulking | 6 | 3 | 3 | 1 | 3 | 2 |
Plt sens/resis/unkn | 10/10/1 | 18/8/1 | NA | NA | NA | NA |
Mean # of prior regimens [# ± SD (Range)] | 3.5 [+1.7(1–6)] | 2 [+1.5(0–6)] | 3.2 [+1.5(1–5)] | 1.8 [+1.5(0–6)] | 4 [+1.9(1–6)] | 2.5 [+1.4(1–5)] |
P < 0.003 | P < 0.025 | |||||
Mean # of cycles Gem/Plt [# ± SD (Range)] | 6.2 [+3.5(1–12)] | 5.44 [+2.5(2–12)] | 6.7 [+3.5(2–12)] | 5.3 [+2.2(2–9)] | 5.2 [+3.0(1–9)] | 6.3 [+3.0(3–12)] |