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Table 3 Summary of toxicity profiles

From: A retrospective evaluation of activity of gemcitabine/platinum regimens in the treatment of recurrent ovarian cancer

Toxicity Profiles Gemcitabine +Cisplatin Gemcitabine + Carboplatin
Overall N = 21 N = 27
Use of rescue antiemetics #(%) 6(29) 1(4)
Use of electrolyte replacement #(%) 5(24) 9(33)
Use of additional IV hydration 7(33) 8(30)
Change in renal function from baseline #(%) 4(19) 1(4)
Change in liver function from baseline #(%) 2(10) 6(22)
Mean dose reductions per patient [# + SD (Range)] 1.9 [+0.7(1–3)] 1.9 [+0.7(1–3)]
Mean treatment delays per patient[# + SD (Range)] 0.8 [+0.9(0–3)] 0.7 [+1(0–4)]
Mean rate of G-CSF administration per patient [# + SD (Range)] 2.9 [+3.3(0–9)] 4.2 [+3.2(0–9)]
Leukopenia, Grade 2 or greater #(%) 0 10(37)
Thrombocytopenia, Grade 2 or greater #(%) 0 2(7)
Neutropenia, Grade 2 or greater #(%) 4(19) 11(41)
  1. Abbreviation: SD Standard deviation