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Table 1 Effect of ML246 and cisplatin on SKOV3 xenograft growth and spread

From: A small molecule inhibitor of the perinucleolar compartment, ML246, attenuates growth and spread of ovarian cancer

Mouse ID Treatment Primary tumor volume(mm3) Lesions outside of primary site (#) Total # extraovarian lesions
201 cisplatin 195.7   0
203 cisplatin 738.2   0
204 cisplatin 70.3   0
205 cisplatin 287.3   0
207 cisplatin 208.9 back/subQ (1) 1
211 cisplatin 25.9 back/subQ (1) 1
214 cisplatin 51.2   0
217 cisplatin NR mouse died  
229 cisplatin NT   0
234 cisplatin 93.3 back/subQ (1) 1
206 vehicle small back/subQ (1) 1
208 vehicle NR mouse died  
209 vehicle 172.6 back/subQ (1) 1
210 vehicle 118.3   0
212 vehicle 11.7 pelvis (1); back/subQ (1) 2
221 vehicle 3.4   0
222 vehicle 35.9 cecum (1); 1
224 vehicle 323.8 diaphram (2); pelvis (1); bowel (1); back/subQ (1); mesentery (1) 6
225 vehicle 184.4 back/subQ (1) 1
223 vehicle 212.0   0
230 vehicle 234.0 bowel (2) 2
233 vehicle small pelvis (1) 1
202 ML246 NR mouse died  
213 ML246 14.3   0
215 ML246 NT   0
216 ML246 140.7 back/subQ (1) 1
218 ML246 NR mouse died  
219 ML246 114.6 back/subQ (1) 1
220 ML246 917.4   0
226 ML246 NT back/subQ (2) 2
227 ML246 NR mouse died  
228 ML246 NT   0
231 ML246 NT   0
232 ML246 213.3   0
  1. NT No tumor, SubQ Subcutaneous, NR Not recorded